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After 9 years, actor Nawazuddin Siddiqui, who was last seen in ‘Secret Superstar’ in 2017, has reentered Bollywood. He has been signed to play the lead in an upcoming and highly anticipated movie ‘Bose: Dead/Alive’.

It was reported that his is set to play the role of Fraternity leader, Kaveri (the daughter of a senior politician).

Nawazuddin Siddiqui in a still from DEAD/ ALIVE

The film that is directed by renowned filmmaker, Sajid Khan and will be produced by Eros Entertainment, it will release in 2019.

He has been seen in films like ‘Harry Potter and the Deathly Hallows Part 2’, ‘Kick’, ‘Dawn’ and ‘Once Upon A Time In Mumbai’.

The movie is in progress in India. There is no official release date yet.Mangiferin attenuates hepatic fibrosis induced by biliary obstruction in rats.
Mangiferin is a natural chalcone and highly appreciated for its various biological properties. This study was aimed to investigate the effect of mangiferin on carbon tetrachloride (CCl4)-induced hepatic fibrosis and the underlying mechanisms. Male Sprague-Dawley rats were administered with CCl4 to induce hepatic fibrosis, and the rats were also orally administered with mangiferin (15mg/kg/day) for 8 weeks. Compared with the model group, mangiferin attenuated CCl4-induced liver fibrosis, reduced the accumulation of lipids and alpha-smooth muscle actin (α-SMA)-positive activated HSCs and promoted the expression of matrix metalloproteinase-2 (MMP-2), tissue inhibitor of metalloproteinase-2 (TIMP-2), N-acetyl-cysteine (NAC)-associated antioxidant capacity, and microRNA-29a (miR-29a), and also enhanced the expression of α-SMA-negative HSC

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